University of California Studies the New Omicron Mutation

The novel coronavirus (SARS-CoV-2) omicron mutation, first discovered in South Africa in November last year, began to spread rapidly around the world from the beginning of this year.

Omicron spread much faster than the original novel coronavirus and caused more breakthrough infections than any other mutation that had appeared before. The same is true for those who have developed immunity from natural infection, or those who have been fully vaccinated, and those who have been pierced by Omicron.

Where does this powerful radio wave of Omicron come from?

Corona mutations before Omicron had many mutations in the spike protein.

However, in the case of Omicron, research results have shown that mutations in the nucleocapsid are the source of strong transmission and immune evasion.

The results of this study conducted jointly by scientists at the Gladstone Institute and the University of California, Berkeley (UC Berkeley) were published as a paper in the Proceedings of the National Academy of Sciences (PNAS) on the 19th.

The co-lead author of the paper, Dr. Melanie Ott of the Gladstone Institute and Professor Jennifer Doudna of UC Berkeley, said that the propagation power of a similar virus with a mutation such as omicron in the spike protein is the same as when a mutation in the spike protein of a lineage upstream mutation occurs. I’m hungry. However, when a mutation such as Omicron occurs, the infectious power is increased by a whopping 30 times.

The neutralizing ability of the antibody was relatively strong in those vaccinated with mRNA. However, mRNA vaccines were also found to be insufficient to prevent delta mutations or omicron mutations.

Plasma from humans 4 to 6 weeks after receiving the mRNA vaccine (38 people in the experimental group size) showed a relatively high neutralizing ability against the ‘ancestral mutation’ (a similar virus) that preceded Omicron. However, the neutralizing ability of the antibody fell to 1/3 for the delta mutation and 1/15 for the omicron. Plasma from those vaccinated with the Johnson & Johnson vaccine or recovered from spontaneous infection showed a lower neutralizing ability than the mRNA vaccine for ‘ancestral mutations’, and there was little difference for delta and omicron mutations. In addition, in the eight subjects who received the Pfizer third-line vaccine two to three weeks later, there were detectable neutralizing antibodies against all mutations.

However, the level of antibodies neutralizing Omicron was only one-eighth of that of other mutated neutralizing antibodies. This means that it is difficult to prevent Omicron mutations with existing coronavirus vaccines, regardless of manufacturer and type.

Monkeypox Symptoms Proving Difficult to Diagnose In the USA

As Monkeypox, a disease endemic to Africa, has spread to other parts of the world, it is difficult to diagnose as it shows different symptoms, Bloomberg News reported on the 22nd (local time).

According to the news, based on the research results published by the medical journal ‘New England Journal of Medicine’ (NEJM).

As a result of analyzing 528 confirmed cases in 16 countries around the world, this study identified patients with rashes in only one area, such as the mouth, anus, and genitals.

This is different from the US Centers for Disease Control and Prevention (CDC) description that rashes occur all over the body, including the face, inside the mouth, hands, feet, chest, genitals, and anus.

“Diagnosis is very important, but we don’t have the ability to actually identify the disease,” said study lead author Chloe O’kin, a professor at Queen Mary University in London.

Some local health authorities have already announced their own symptoms of Monkeypox and other symptoms.

The New York City health authorities explained in a notice on the 18th that some confirmed cases had a short incubation period of 2 to 5 days, unlike general infection cases, did not have high fever or enlarged lymph nodes, and only slight lesions appeared in the anus and genital area.

Co-author John Thornhill, a professor at Queen Mary University, said, “The symptoms different from the previous ones mean that Monkeypox infection cannot be confirmed, or it can be misdiagnosed as common sexually transmitted diseases such as syphilis and herpes. said.

Monkeypox, found historically in West and Central Africa, spread mainly through contact with infected animals or with infected households.

However, in Europe and the United States, contact between homosexual men is the main route of spread.

Most of the cases analyzed in this study were also gay or bisexual men who had sex with other men.

Monkey smallpox is known to be more severe in people with AIDS, but no such difference was detected in this study.

At present time, Monkeypox has not been classified as a sexually transmitted disease.  It has not been determined if it is transmitted through sexual fluids such as semen.

The study found the virus in 29 of 32 semen samples but was not confirmed to be contagious.

Contrary to the government’s promise, there is currently a shortage of vaccines and treatments in some parts of the United States.

As a result, some people are reminded of the 1980s, when AIDS patients had no choice but to wait and wait because it was difficult to obtain a drug, Bloomberg said.

Las Vegas Drought Limits Size of Swimming Pools in New Homes

Las Vegas, the ‘pleasure city’ in the US desert, has decided to limit the size of new swimming pools in homes after severe water shortages.

According to foreign media such as the AP and the New York Post on the 23rd, the Clark County Congress in the US state of Nevada, where Las Vegas belongs, has recently passed a new regulation that sets the maximum area of ​​a new swimming pool in a private house to 56 square meters.

It is about the size of three passenger cars and will be implemented from September 1. This rule does not apply to existing swimming pools.

Residents who violate the rules will be subject to ban.

Clark County has a population of 2.4 million and more than 1,300 new swimming pools are built each year. There are currently 200,000 swimming pools in private homes, the Associated Press reported.

However, resorts and hotel swimming pools are also not affected by this rule, as they already have area restrictions.

The industry sees it as the first case in the United States to impose size restrictions on swimming pools in private homes.

“It was a tough decision,” Clark County Council Chairman Jim Gibson said.

In fact, the United States is suffering from a drought mainly in the western region.

According to satellite images released by the National Aeronautics and Space Administration (NASA), in the case of the Colorado River Mead, the western ‘lifeline’, the water level this month was 317.60 m, which is close to 50 m lower than 365.76 m in 2000.

This is the lowest level since April 1937, when Lake Mead was filled with water.

The U.S. government expects that the water level in Lake Mead, which supplies water not only to Nevada, but also to seven states including Arizona and California, and northern Mexico, will drop by another 6 meters next summer.

The Southern Nevada Water Authority estimates that the Clark County resolution could save 12 million liters of water in the first year alone and 121 million liters by 2032.

However, the New York Post pointed out that the amount of water being saved is not much considering the amount drawn from Lake Mead (344 billion liters) each year.

Authorities, however, have also decided to require other county legislatures to limit pool area.

The local industry also seems to resist, saying that the effect of limiting the swimming pool area will be insignificant.

An official at a swimming pool company said, “The swimming pool is a part of life for Las Vegas residents,” the AP reported.

Locals and Tourists Warned to Be Careful Driving on Route 66

Recently, there are a lot of complaints from drivers using Virginia Route 66, such as blown tires and broken windshields. Tires often have nails or screws stuck in them, so they go to a repair shop, and stones or metal objects that have fallen on the road crash into the windshield in many cases.

As things that are supposed to happen once or twice in a few years have occurred frequently in recent years, many drivers attribute the cause to the construction of Route 66. The number of large trucks and construction vehicles has increased and the road has become messy, but it is pointed out that it is not cleaned properly due to the high volume of traffic.

“For the past several years, I took Route 66 to work every day on the same route, but there were two punctures in the last month alone,” said a resident who commutes from Centerville to Annandale. .

When he told his co-worker just in case, he said, “Recently, other people have had punctures and cracks in the glass.” He concluded that “No. 66 was the culprit.”

Road 66 has been under construction for several years, but there have been no complaints about the number of vehicles over the past two years due to the pandemic. However, recently, as the number of vehicles increases again, traffic congestion becomes more serious, and the number of nails and screws being pierced in construction sections is increasing, causing complaints to increase.

Tire repairs or windshield replacement are not expensive, so most of them are not covered by insurance and have to pay the repair costs themselves. Such unexpected expenses are burdensome, and above all, it is difficult to change tires suddenly and wait for a tow truck.

A Korean who suffered damage while driving on Route 66 said, “It is inconvenient and annoying, but I will avoid Route 66 and return to the local road for the time being.”

New York and New Jersey Dominates ‘BA.5’ – Omicron Sub-Variant

In New York and New Jersey, it was also found that the corona 19-micron sub-variant ‘BA.5’ was established as the dominant species. Due to immunity evasion and strong transmission power, the possibility of a COVID-19 resurgence this summer is at an emergency.

According to the Federal Centers for Disease Control and Prevention (CDC), BA. This is a marked increase from the 52% from June 26 to July 2 a week ago.

BA.5 is a sub-mutation of the Omicron mutation that led the COVID-19 pandemic earlier this year. However, it is highly contagious enough to be called the worst version of Omicron. It is known that the transmission power of BA.5 is 50% stronger than that of Omicron mutation, and there is concern about re-infection because it has the property of well avoiding the immunity acquired after vaccination or natural infection.

According to a recent Columbia University study, the BA.5 mutation is 4.2 times more resistant to vaccine than the previous mutation.

According to the New York State Government, the risk of reinfection is increasing in New York State overall, but Long Island has the highest reinfection rate at 7.3 per 100,000 people.

New York City ranked second with 6.9 per 100,000 residents. Moreover, New York City has a new incidence rate of 41 per 100,000, higher than Long Island, and all five New York City boroughs are designated as high-risk areas by the CDC.

New Jersey is also rapidly spreading since the BA.5 mutation was first discovered on May 28.

The New Jersey state government announced on the 13th that 1,013 COVID-19-related hospitalizations across the state were the highest since February 20.

The CDC has assigned a high risk of COVID-19 to six counties in New Jersey: Morris, Burlington, Camden, Atlantic, Cape May and Manmouth.

Full-Scale Inspection by a Private Company for Monkey Pox

As monkey pox cases are on the rise worldwide, the United States has begun to expand testing through private diagnostic companies.

The Centers for Disease Control and Prevention (CDC) announced on the 6th (local time) that Labcorp, a private diagnostic test company, will start testing for monkey pox from today.

The United States has been criticized for insufficient number of tests while testing suspected patients through public health facilities. In response, the health authorities have been preparing to expand the test so that private diagnostic test companies can use CDC reagents.

The U.S. Department of Health and Human Services announced on the 22nd of last month that Lapcorp and five other testing companies would soon test for monkey pox.

The company conducts the test using the Orthopoxvirus reagent, which belongs to the virus family to which monkey pox belongs, owned by the CDC.

The CDC’s reagent will detect all non-smallpox true smallpox viruses, including monkey pox, and Labcorp said it will have the ability to perform more than 10,000 tests per week.

“All testing will first be conducted at our largest facility in North Carolina, with testing expanded to other locations as needed,” Labcorp’s chief medical officer, Brian Kavney, said in a statement. Labcorp receives samples from all over the country and tests them.

The CDC said that Labcorp’s incorporation of diagnostic testing will double the testing capacity.

The CDC recommends that anyone who presents a rash that appears to be monkeypox should seek immediate health advice by speaking with their health care provider even if they think they haven’t had contact with an infected person.

If it is determined that the test is necessary, the medical staff must order a test device from Labcorp and send a sample from the suspected patient to Labcorp to be tested positive.

Currently, more than 550 cases of monkey pox have been confirmed in 33 states in the United States, Washington, D.C., and Puerto Rico.

Fate of DACA – Deportation Deferred for Undocumented Youth

A federal appeals trial that will decide the fate of the Deferred Action for Undocumented Youth (DACA) program is starting in earnest.

The 5th Circuit Court of Appeals for the Federal Circuit will begin a two-week hearing on whether DACA is unconstitutional from the 6th.

In July of last year, a Texas District Court ruled that the DACA program was illegal, ordering it to stop accepting new DACA applicants.

The outcome of this appeal will affect whether DACA is legal, as well as the resumption of processing for new applicants.

The DACA program, introduced as an executive order by the Barack Obama administration on June 15, 2012, has been evaluated to have prevented the deportation of undocumented youth, called “dreamers,” and opened the way for them to continue their studies and employment.

However, DACA has been engulfed in litigation over the past decade and has been on the verge of extinction. It has been a constant target of opponents of DACA because it is based on an executive order that has not been passed through the legislative process in Congress.

In August of last year, Texas District Court Judge Andrew Hannon ruled in favor of the plaintiff in a DACA lawsuit filed against the federal government by nine states, including Texas.

However, while Judge Hannon ruled that DACA was illegal, it maintained protections for existing beneficiaries. As a result, the approval of new DACA applicants is currently suspended, but existing DACA beneficiaries will continue to receive deferred deportation and work permits and can be renewed every two years.

Immigration law experts expect the legal battle over DACA will eventually reach the Supreme Court. In 2020, the Supreme Court ruled to maintain DACA, but this did not deal with the legality of DACA itself, but rather on whether the former administration of Donald Trump’s attempt to repeal DACA was legal.

At the time, the Supreme Court upheld DACA, 5-4, arguing that the Trump administration had failed to provide a proper reason for repealing DACA.

However, unlike at the time, the current composition of the Supreme Court is composed of 6 conservatives and 3 liberals, and the Supreme Court is predominantly conservative. For this reason, there is a concern that if the appeal court finds that the DACA is unlawful, the Supreme Court may also make an unfavorable decision.

The surest way for DACA to survive is for the federal legislature to take legislative action but given the stalemate in the political circles ahead of the midterm elections in November, the common view of the US government is that it is unlikely to materialize within this year.

How to Prepare for a Summer Vacation with Young Children

An outing with young children can be overwhelming if you have not prepared and not ready for all possible unexpected situations.

What to prepare for your baby when traveling?

Transportation: Unlike adults, young children do not understand and do not have the patience for long trips with nothing to do. Prepare enough toys to buy time while traveling or download animated videos and children’s music for your children to watch, avoiding the case of not being able to access the internet.

In addition, you can time your travel at the right time for your child to sleep so that he or she does not stay awake during the whole bus or flight. Prepare enough food, water, earplugs, thin coats, pack diapers for your child in case. Remember to let your child go to the toilet before boarding the train or plane. This will limit the ability of the baby to cry and cause fatigue for themselves as well as those around them.

Parents need to prepare plans or find suitable food for their children at the destination. Parents can also choose accommodations that can use a kitchen or have a food warmer for their children for the family to use when needed.

Clothing: It is necessary to monitor the weather forecast at the destination to prepare suitable clothes for the baby, to avoid unexpected hot or cold weather.

Medicines: It is necessary to have ready-made medicines that children often use to respond promptly when encountering simple health problems caused by sudden changes in the environment, the amount of exercise as well as eating. Especially for children who have health problems or often have health problems.

Recreational activities for children: A rememberable trip not only require entertainment activities for adults, but also activities and experiences for children. A fun and meaningful trip for the whole family needs a lot of suitable and meaningful programs for all objects in the family.

The Future of ‘Cheap’ Sleeper Cabins is Common on Airplanes

Bed compartments are already quite common equipment on 4-wheel vehicles, but for airplanes, this is still an extremely luxurious option.

On large tourist buses, it is easy to access to a bed or to a sleeper compartment with a small amount of money for long journeys.

However, if you want to access the same amenities on the plane, users have to choose certain airlines, certain routes and have a good account, because this type of comfort on the air is still extremely expensive.

For example, Emirates First Class tickets on an Airbus A380 from New York to Dubai cost $14,705 compared to $960 in economy class and $4,535 in business class.

Last week, Air New Zealand said it will put into use a pilot cabin model for long-haul passengers on Boeing 787 aircraft from 2024 onwards.

Each user will have 4 hours of reclining in the cabin, the average aircraft has a cabin with 6 beds (2 beds with 3 floors) with many utilities such as reading lights, USB charging ports, separate air vents, headphones. , mattress/blanket/pillow.

After each passenger use, the crew will replace all used mattresses, blankets and pillows for the next user. With a long flight, the number of passengers using the bed can be up to 4 times. Basically, this model is quite similar to the “mini-cabinets” that we can see at some airports around the world.

Air New Zealand has not announced the above service price list, but the cost is not expected to be too expensive. They also hope that the implementation of this service can push international airlines to apply similar services to serve users at an even higher level in the future.

6 Months Home Detention for a Punching Flight Attendant

A man charged with assaulting a flight attendant who was drying the thigh of a woman seated next to him on a flight from Seattle has been sentenced to home detention and fines for months.

Two U.S. judges, Miranda, ruled that 41-year-old David Parkhurst was held at home for six months and awarded $49,000 in damages for assault and obstruction of business. In addition, he was sentenced to five years of probation.

Parkhurst, a resident of Gardnerville, Nevada, groped the inner thigh of a female passenger seated next to her on a flight from Seattle to Las Vegas on October 31, 2019, without permission.

When the woman noticed this and stopped him by slapping his hand, she began to assault the woman, including punching her, and the flight attendant rushed in and pulled him off the woman.

After that, considering the safety of passengers, the plane made an emergency landing at Renault-Tahoe International Airport before arriving in Las Vegas, where it was originally scheduled, and handed over Parkhurst to the police.

Parkhurst pleaded guilty in February for obstruction of duty and simple assault on the plane.